Is it possible for somebody to achieve testosterone suppression through sublingual Estradiol tablets? I know that in theory you should be able to just take several tablets a day but I was wondering if anybody else had chosen this route?

    • dandelion
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      12 hours ago

      What I’ve heard about patches is that it can be difficult to get your estrogen high enough with them (for monotherapy at least). I’ve also heard other problems like rashes, the patches falling off too early (and being expensive to replace), and needing too many to make monotherapy reasonable.

      Again, why not injections?

      • florenciaOP
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        10 hours ago

        In my opinion, injections are the gold standard. I just wanted to know if sublingual monotherapy was a possibility and if anybody had accomplished it.

      • femtech@midwest.social
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        10 hours ago

        All at once, I don’t want to stab myself, easier to put one on twice a week so I don’t forget when lazy/tired. ESTRADIOL 0.1 MG PATCH (2/WK) is what I have.

        • dandelion
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          8 hours ago

          One 0.1 mg patch isn’t enough for monotherapy, but you could try multiple patches for monotherapy. What are you estradiol blood levels like with that dose?

          I don’t like stabbing myself either, but the benefits of injections outweigh those concerns (and I have done a lot to mitigate my needle phobia).

          • femtech@midwest.social
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            7 hours ago

            Well my hormones were off before I started and I’m post op now. My T before starting was 375 and my Estrogen total was 250. Now my T is 4 and my ESTRADIOL (E2) is 40

            • dandelion
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              7 hours ago

              oh interesting, yeah - I am pre-op, so I am relying on monotherapy to suppress my T.