So for starters, this is specifically for B12. Not intentional, as my point applies to all powder pills, but sure as shit topical.
Article details dietary B12, an equivalent intake pill B12 supplement, and a 4x intake pill B12 supplement.
The dietary? Restored the deficiency.
The 2 pills? Not only signifigantly less effective, but also almost equivalently so.
Thats insane. I assumed that quadrupaling the dose would improve the intake, its just a huge waste of money to eat 4-8 vitamin pills a day. But the study shows a quadruple dose is completely ineffective!
Also, (and I skimmed this specific bit from the results) it seems that the pill based intake was primarily in the liver. Now, the study correctly makes no causational link here, but that lightly implies that the liver is filtering out supplementals rather than letting it enter the dietary process. No clue if thats true, but a big possibility that I hope gets looked into further.
(Article also implies its not the powder pill form but rather the dietary type used in the pill. But it doesnt isolate powder sources of both versions of B12, so thats not conclusive.)
So, uh. Yeah. Big research article for you, the pill doesnt do shit, eating more of them also doesnt do shit, you need to be eating it in the food.
And yet it does improve B12 levels sufficiently to resolve what would be a deficiency for rats.
I never claimed that dietary nutrients don’t have a better uptake.
In addition, while rats and humans are similar, it’s still done on rats and not humans. Maybe instead of a daily pill the rats needed a pill twice a day? And if we were rats that’s what would recommendation would be? After all, rats need a lot more B12 than we do. In addition, this was just 6 weeks. Maybe given sufficient time both methods work just fine? You should note that even the dietary B12 failed to raise B12 levels back to the original value. The timescale may just be too short.
Sure, interesting study, but it’s not conclusive for humans.
The study literally demonstrated that a quadruple dose only provided a partial effective intake for the liver and failed to provide enough for the brain, and you think a double dose would work? The kook strikes again!
Also, you understand that rats are used for nutrient studies because our digestive systems are insanely similar? “Hurr but Im not a rat” hasnt been a real rebuttal in a century.
Wild, who would have guessed the blood test kook would deny peer reviewed evidence. Oh, shit, it was me? I called that? Gnarly. Guess I was right, giving you the link was a waste of time.
Cited about what? That study appears to be about diagnosing cause of specifically B12 deficiencies and response to injections, which 1) has nothing to do with powder pill vitamin intake and 2) is talking about malabsorption, not suplementation of an intentionally abandoned dietary intake.
If you want to talk about a study, you need to say what your context is. Lol who am I kidding, the kook doesnt give a shit about science
Hey, actually? I got super lucky with the first article I found.
https://www.mdpi.com/2072-6643/10/8/1096
So for starters, this is specifically for B12. Not intentional, as my point applies to all powder pills, but sure as shit topical.
Article details dietary B12, an equivalent intake pill B12 supplement, and a 4x intake pill B12 supplement.
The dietary? Restored the deficiency.
The 2 pills? Not only signifigantly less effective, but also almost equivalently so.
Thats insane. I assumed that quadrupaling the dose would improve the intake, its just a huge waste of money to eat 4-8 vitamin pills a day. But the study shows a quadruple dose is completely ineffective!
Also, (and I skimmed this specific bit from the results) it seems that the pill based intake was primarily in the liver. Now, the study correctly makes no causational link here, but that lightly implies that the liver is filtering out supplementals rather than letting it enter the dietary process. No clue if thats true, but a big possibility that I hope gets looked into further.
(Article also implies its not the powder pill form but rather the dietary type used in the pill. But it doesnt isolate powder sources of both versions of B12, so thats not conclusive.)
So, uh. Yeah. Big research article for you, the pill doesnt do shit, eating more of them also doesnt do shit, you need to be eating it in the food.
And yet it does improve B12 levels sufficiently to resolve what would be a deficiency for rats.
I never claimed that dietary nutrients don’t have a better uptake.
In addition, while rats and humans are similar, it’s still done on rats and not humans. Maybe instead of a daily pill the rats needed a pill twice a day? And if we were rats that’s what would recommendation would be? After all, rats need a lot more B12 than we do. In addition, this was just 6 weeks. Maybe given sufficient time both methods work just fine? You should note that even the dietary B12 failed to raise B12 levels back to the original value. The timescale may just be too short.
Sure, interesting study, but it’s not conclusive for humans.
As a last note, the study that seems to be most commonly cited is https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532799/
The study literally demonstrated that a quadruple dose only provided a partial effective intake for the liver and failed to provide enough for the brain, and you think a double dose would work? The kook strikes again!
Also, you understand that rats are used for nutrient studies because our digestive systems are insanely similar? “Hurr but Im not a rat” hasnt been a real rebuttal in a century.
Wild, who would have guessed the blood test kook would deny peer reviewed evidence. Oh, shit, it was me? I called that? Gnarly. Guess I was right, giving you the link was a waste of time.
Cited about what? That study appears to be about diagnosing cause of specifically B12 deficiencies and response to injections, which 1) has nothing to do with powder pill vitamin intake and 2) is talking about malabsorption, not suplementation of an intentionally abandoned dietary intake.
If you want to talk about a study, you need to say what your context is. Lol who am I kidding, the kook doesnt give a shit about science