Estradiol monotherapy. Started HRT 3 months ago with 2mg Estradiol oral tablets. Have a doctor appointment in a few days and wanted to ask to double my oral prescription, split up 4mg into 4 doses sublingual every day. Not sure if my Estrogen levels are too high and my doctor will deny my request.

  • Pre-HRT Estrogen (TOTAL IA): 181 pg/mL
  • Pre-HRT Testosterone (Total IA): 246 ng/dL
  • Levels this week Estrogen Total IA: 438 pg/mL
  • Levels this week Testosterone Total IA 115 ng/dL

From what I understand I feel like I’m definitely not achieving Testosterone suppression. https://transfemscience.org/ recommends T levels around 10 ng/dL. But having E levels of 400 pg/mL is the right range for E.

Can I convince my doctor to double my dose if my E is already at >400 pg/mL?

Edit 01: I did not take my daily dose until after my blood was drawn. Blood draw was already 24+ hours since last oral dose.

  • fiohnah
    4·
    23 hours ago

    Adding Progesterone can help get the Testosterone levels down considerably without adding Estrogen. The administration route doss matter a lot. You just need to decide if it’s too early to start. I attached a screenshot of my own levels and what I was taking at each point. Keep in mind the top graph is log scale and these are just my personal results.

    Edit: There are no units listed because this was for me to show my doctor asking with my labs and not for the Internet. The important thing is how the levels changed. Estradiol Valerate strength was 5mg/mL.