Breast Development in Transwomen After 1 Year of Cross-Sex Hormone Therapy: Results of a Prospective Multicenter Study
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This prospective multicenter study shows that the gained breast development after the first year of CHT in transwomen was modest and occurred primarily in the f

Breast Development in Transwomen After 1 Year of Cross-Sex Hormone Therapy: Results of a Prospective Multicenter Study

Mean breast-chest difference in centimeters over duration of CHT in months. For each time point, the mean increase in centimeters (dot) with 95% CI (bars) is shown. Data in the legend are shown as mean increase with 95% CI.

Mean breast-chest difference in centimeters over duration of CHT in months. For each time point, the mean increase in centimeters (dot) with 95% CI (bars) is shown. Data in the legend are shown as mean increase with 95% CI.

Gained bra cup sizes in 197 transwomen after 1 year of CHT. Data are shown as percentage of transwomen per cup size.

Gained bra cup sizes in 197 transwomen after 1 year of CHT. Data are shown as percentage of transwomen per cup size.

Mean breast-chest difference in centimeter over duration of CHT in months, stratified for age in four groups. (a) Weight change in three groups (b), normal weight (BMI < 25 kg/m2), overweight (25 kg/m2 ≥ BMI > 30 kg/m2), and obese (BMI ≥ 30 kg/m2) BMI (c), smokers vs nonsmokers (d), oral vs transdermal estradiol administration route (e), and four quartiles of serum estradiol levels (f). Mean serum estradiol levels in the center-specific quartiles were 110 pmol/L−1 (first quartile), 184 pmol/L−1 (second quartile), 271 pmol/L−1 (third quartile), and 452 pmol/L−1 (fourth quartile) in Amsterdam, and 142 pmol/L−1 (first quartile), 206 pmol/L−1 (second quartile), 299 pmol/L−1 (third quartile), and 567 pmol/L−1 (fourth quartile) in Ghent. For each time point, the mean increase in centimeters (dot) with 95% CI (bars) is shown.

Mean breast-chest difference in centimeter over duration of CHT in months, stratified for age in four groups. (a) Weight change in three groups (b), normal weight (BMI < 25 kg/m2), overweight (25 kg/m2 ≥ BMI > 30 kg/m2), and obese (BMI ≥ 30 kg/m2) BMI ©, smokers vs nonsmokers (d), oral vs transdermal estradiol administration route (e), and four quartiles of serum estradiol levels (f). Mean serum estradiol levels in the center-specific quartiles were 110 pmol/L−1 (first quartile), 184 pmol/L−1 (second quartile), 271 pmol/L−1 (third quartile), and 452 pmol/L−1 (fourth quartile) in Amsterdam, and 142 pmol/L−1 (first quartile), 206 pmol/L−1 (second quartile), 299 pmol/L−1 (third quartile), and 567 pmol/L−1 (fourth quartile) in Ghent. For each time point, the mean increase in centimeters (dot) with 95% CI (bars) is shown.

  • @BlueSharkEnjoyerEnglish
    4•1 year ago

    One of the other confounding factors potentially is that this is from those who first got HRT from gender clinics, so would exclude those who were driven to self-med or go private.