Compare the amount of protein that is in a flu shot (60 micrograms in Fluzone at most) to a typical mAb (~150 mg up to 1 g at most), you can see how much less the vaccine requires
And with mRNA you get extra amplification from each mRNA being translated multiple times. Then again an mRNA is a lot more massive than its protein product.
And with mRNA you get extra amplification from each mRNA being translated multiple times. Then again an mRNA is a lot more massive than its protein product.