You can interpret words literally. However human organisms use literal interpretation and context to communicate meaning without saying it literally. In the original comment saying MOST females won’t get the joke is incorrect in a literal interpretation. Furthermore the use of “female” with this literal statement in MOST people’s interpretation is commonly associated with sexist (doesn’t have to be hate, just dislike in general) attitudes against women. (The quote “women, am I right?” Comes to mind as a similar sentiment.) This interpretation is learnt by everyone whom exist outside of the internet and is learnt from society to prevent conflict and unwanted hate, there’s no need to feel paranoia about reading it when the literal text and common interpretation of the text reads as a degrading attack on MOST females. (The meme touch grass is intended for instances like this.)