Before Long Covid there was post-viral fatigue – a mysterious set of illnesses caused by other infections. Now scientists are starting to unravel their secrets.

Summary

Post-viral fatigue,* a mysterious illness linked to infections such as Epstein-Barr, Ebola, and Lyme disease, has long been poorly understood.

Scientists are now investigating its underlying causes, including mitochondrial dysfunction, inflammation, and autoimmunity, while exploring potential treatments like enzyme supplements and repurposed medications.

Current studies are focusing on repurposed HIV drugs, enzyme therapies, and supplements such as Coenzyme Q10.

Identifying at-risk subgroups and uncovering the mechanisms behind fatigue could produce targeted clinical trials and new treatments within the next 1-2 years.

EDIT:

*Should be post-acute infection syndrome or myalgic encephalomyelitis instead (thanks @FundMECFSResearch@lemmy.blahaj.zone)

  • FundMECFSResearchEnglish
    10·
    4 hours ago

    “fatigue” being in the name was one of the reasons it used to be dismissed as psychological.

    But now, especially with the help of long covid, we’ve found a distinct clinical entity, with clear physical markings, Complement system overractivation, T-cell exhaustion, WASF3-caused mitochondrial dysfunction etc.