Temperatures Friday night and early Saturday in traditional hot spots such as Shreveport, Louisiana; Jackson, Mississippi; Birmingham, Alabama; and Atlanta are set to dip into the low 20s or teens.

The weeklong Arctic cold that’s blanketed much of the nation has taken more than 50 lives, officials said, as 66 million people in the United States are under winter weather warnings Friday.

Wind chill alerts Friday afternoon stretched from Montana to Florida and freeze alerts remained in effect across the South and Gulf Coast.

Temperatures Friday night and early Saturday in traditional hot spots such as Shreveport, Louisiana; Jackson, Mississippi; Birmingham, Alabama; and Atlanta are set to dip into the low 20s or teens.

Wind chill alerts Friday afternoon stretched from Montana to Florida and freeze alerts remained in effect across the South and Gulf Coast.

Of the 51 cold-related deaths since last Friday, 17 happened in Tennessee, nine in Oregon, six in Illinois, five in Washington state and Mississippi, three in New York state, two in Louisiana and one each in Arkansas, Wisconsin, Wyoming and New Hampshire, local and state officials have told NBC News.