With all the hormones and whatnot inside. Dopamine, adrenaline, melatonin, whatever. Also, there’s this Hunter S. Thompson bit on the… pineal gland?

If it had an effect on you, wouldn’t it be a really messed up high, all over the place? With uppers, downers etc mixed? (Not including the emotional implications of eating raw human brains.)

  • GingaNinga@lemmy.world
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    1 year ago

    no your stomach acid would denature most of the proteins, then they’d be conjugated at the liver so whatever goes in will be transformed by what comes out. A lot of those hormones are tightly regulated so I’m thinking even if they make it into circulation they’d be eliminated fairly quickly. Only exception would be if they’re acid stable, not impacted on their way through the gut/metabolised by microbiota, absorbed in tact and still active after the first pass effect. Also theres enzymes like trypsin in your stomach that are specifically for degrading proteins so I doubt it would make you anything other than a canibal.

    • Sethayy@sh.itjust.works
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      1 year ago

      Would smoking raw human brains make you high?

      Wait no thermal degredation

      Would nebulizing raw human brains make you high? Especially of I got a little brain-diffuser in the corner that just filled the room with the aroma

    • set_secret@lemmy.world
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      1 year ago

      you’re mostly right, however trypsin is produced in the pancreas and excreted into the duodenum, so not in the stomach. I think maybe you’re thinking of pepsin?

      • GingaNinga@lemmy.world
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        1 year ago

        The liver “conjugates”/metabolises a bunch of stuff, its been almost a decade since I studied this stuff but bassically it will remove or add functional groups on/off a given compound. Most of what you eat heads straight to the liver for “processing” where food (and orally administered drugs) get altered prior to circulation. Its part of the first pass effect.