With all the hormones and whatnot inside. Dopamine, adrenaline, melatonin, whatever. Also, there’s this Hunter S. Thompson bit on the… pineal gland?

If it had an effect on you, wouldn’t it be a really messed up high, all over the place? With uppers, downers etc mixed? (Not including the emotional implications of eating raw human brains.)

  • sir_pronoun@lemmy.worldOP
    link
    fedilink
    English
    arrow-up
    8
    ·
    1 year ago

    I used to think that these hormones might break down in stomach acid as well, but then I discovered melatonin fruit gummies, which supposedly help you sleep. These gummies are what really inspired this question. (The ones I have are mango flavored, not brains flavored, btw, in case you were wondering)

    • Norgur@kbin.social
      link
      fedilink
      arrow-up
      10
      ·
      1 year ago

      Melatonin also breaks down in your stomach. It’s absorbed through the mouth and tongue while chewing. After that, most of the rest is lost. That’s why Melatonin pills require higher doses to do anything. The medical science world is still split if any of the fancy melatonin you gobble up in all those gummies can cross the blood brain barrier at all.

      So the same rules apply.

      • roguetrick@kbin.social
        link
        fedilink
        arrow-up
        3
        ·
        edit-2
        1 year ago

        Overall its very inconsistent due to the first pass effect of the liver as well. Anything absorbed from the alimentary canal goes through the liver first and the liver is very effective at breaking down lost hormones.

    • alvvayson@lemmy.world
      link
      fedilink
      arrow-up
      8
      ·
      1 year ago

      I think melatonin is more the exception than the rule.

      Testosterone needs to be injected and has a very short half life.

      A quick Google shows Dopamine also needs to be injected and has a half life of one minute, so is only used as an IV drip.