Star Trek celebrates the diversity of humanity. The extremes of genetic engineering and (on the other side of the spectrum, perhaps) the Borg are symbolic of the corruption of that diversity.
For an in-universe explanation, I suppose you could just look at the degree to which cybernetics are tolerated. Rutherford-level cybernetics? No problem! Borg Queen-level cybernetics? Helm, warp nine, full reverse!
Generally even ex-Borg, like Seven of Nine, aren’t disliked or mistrusted because of their remaining cybernetic implants. It’s almost always about their connection too, and implied complicity in, horrors and genocide.
Star Trek celebrates the diversity of humanity. The extremes of genetic engineering and (on the other side of the spectrum, perhaps) the Borg are symbolic of the corruption of that diversity.
For an in-universe explanation, I suppose you could just look at the degree to which cybernetics are tolerated. Rutherford-level cybernetics? No problem! Borg Queen-level cybernetics? Helm, warp nine, full reverse!
The Bynar are very tied in like the borg but it is all willing and for the most part they retain individuality at least down to the couples level.
Only reason the Borge are hated is the forced joining that removes individuality. The federation likely has no issue with the whole cyborg part.
Generally even ex-Borg, like Seven of Nine, aren’t disliked or mistrusted because of their remaining cybernetic implants. It’s almost always about their connection too, and implied complicity in, horrors and genocide.