Scientists at UC Riverside have demonstrated a new, RNA-based vaccine strategy that is effective against any strain of a virus and can be used safely even by babies or the immunocompromised.
  • mipadaitu@lemmy.worldEnglish
    88·
    10 months ago

    This sure sounds like an amazing breakthrough, RNA based vaccine that works on “all strains” of a virus and can be administered with a nasal spray…

    Would be pretty amazing to not have to go get a shot annually, just a quick nose spray once and be done.

    • Bipta@kbin.social
      93·
      10 months ago

      Most promises in medical news, much like energy news, never pan out.

      Here’s to hoping though.

      • RGB3x3@lemmy.worldEnglish
        22·
        10 months ago

        In medicine, finding out what doesn’t work is nearly as valuable as finding what does. Because finding out why it doesn’t work can lead to you the solution and perhaps even solutions for things you weren’t even looking for.

        • FilterItOut@thelemmy.clubEnglish
          3·
          10 months ago

          finding out what doesn’t work is nearly as valuable as finding what does

          Sometimes, sure. Most of the time, though, it’s more akin to: “Worked on isolated cells in vitro, but doesn’t approach target cells in vivo due to ECM.”

    • MyDogLovesMe@lemmy.worldEnglish
      11·
      10 months ago

      Ya. Until the kooks decide Bill Gates is resting to install AI in our heads through our noses. …or some such bullshit.

  • Daxtron2@startrek.websiteEnglish
    31·
    10 months ago

    It will be awesome if this can make it to human trials and be successful. Lots of immunocompromised people could benefit from this.

  • iAvicenna@lemmy.worldEnglish
    23·
    10 months ago

    Website says

    "Scientists at UC Riverside have demonstrated a new, RNA-based vaccine strategy that is effective against any strain of a virus and can be used safely even by babies or the immunocompromised. "

    Paper says

    “Live-attenuated virus vaccine defective in RNAi suppression induces rapid protection in neonatal and adult mice lacking mature B and T cells”

    I love how they probably used chatgpt to summarize the article for their website. And jumping from here to saying “this vaccine is effective against everything ever” seems a bit! over reaching. Even universal vaccines within a given subtype are finicky. There seems to be a trade off between universality (of recognition) and of effectiveness. Nevertheless this seems like a different mechanism than previous RNA/protein vaccines in that it seems to work by inducing innate immunity. Even though they say that mice remain immune 90d post vaccination, that is another area where mice and men can be substantially different, so I think we are still at the wait and see stage unfortunately.

    And this joke of a sentence here

    "With one vaccine injection, they found the mice were protected from a lethal dose of the unmodified virus for at least 90 days. Note that some studies show nine mouse days are roughly equivalent to one human year. "

    Wohooo we are immune for 10 years!!!

    • Atelopus-zeteki@kbin.run
      4·
      10 months ago

      I can’t seem to find the paper, either. Hmmm… where 'tis? I emailed the article author, Jules Bernstein, to request a link fix. fingers crossed.

      • Sludgehammer@lemmy.worldEnglish
        4·
        10 months ago

        Link works for me maybe they fixed it?

        If you want to search for it yourself it’s “Live-attenuated virus vaccine defective in RNAi suppression induces rapid protection in neonatal and adult mice lacking mature B and T cells” by Gang Chen, Qingxia Han, Wan-Xiang Li, and Shou-Wei Ding

        • Atelopus-zeteki@kbin.run
          2·
          10 months ago

          Today it worked fine. Could be on my end. VPN, script blockers, etc. shrug

          And WOW this looks like a significant development.

      • uhmbah@lemmy.caEnglish
        3·
        10 months ago

        I’m not anti vac. But, this article is pretty smug while still using the word “should”. Hubris is thinking that we’ve beat nature.

        I’m absolutely thrilled if this actually gets us to the next level of protecting people. But I’m beating down by these “savior” articles.