From knowyourmeme.com:

The Hawk Tuah Girl, also known as the Spit On That Thing Girl or Spit On That Thang Girl, refers to a woman who was interviewed in a viral TikTok video and was asked, “What’s one move in bed that makes a man go crazy every time?” to which she responded in a Southern accent, “Oh, you gotta give him that hawk tuah and spit on that thang,” resembling a spitting sound amid oral sex.