The largest ever real-world study found PrEP to work extremely well as a preventative treatment.

A drug which stops HIV infecting the body has proved to be a highly effective “real-world” preventative treatment, a study has confirmed. The results of the research on 24,000 people taking it across England, have been described as “reassuring”.

Thousands of people are already taking PrEP through sexual health clinics.

HIV charity the Terrence Higgins Trust wants easier access to the drug, since many people, including women, do not know it exists.

The UK Health Security Agency (UKHSA), which led the PrEP Impact Trial with the Chelsea and Westminster Hospital NHS Foundation Trust, said it was the largest ever real-world study of its kind. Funded by NHS England, it was carried out at 157 sexual health clinics across England between October 2017 and July 2020.

The study found use of PrEP, also known as pre-exposure prophylaxis. reduced the chances of getting HIV by around 86% when used in everyday life - taking into account inconsistent or incorrect use. Clinical trials suggested the medication is 99% effective.

  • @mjsaber
    8•7 months ago

    That’s not entirely true. Receptive vaginal sex is much less likely to transmit the virus than anal sex (about 17x less). Insertive anal sex is more likely to transmit than vaginal sex, too, so the type of sex you have matters too.

    Number of partners, and their sexual habits really matter, too. It’s important to help people really understand their STI risk if we want people to make healthier decisions regarding sex.

    • @tsonfeir@lemm.ee
      8•7 months ago

      Please don’t share this misinformation,

      because you’re anti-gay, or you’re under the impression that HIV is a gay thing.

      By the numbers, more heterosexual people have HIV than homosexual people. Not by the percentage of the community, which is a right-wing nonsensical way to blame gay people.

      It has nothing to do with the “STI risk,” as if it’s some kind of range. If a PERSON of ANY GENDER is having unprotected sex with people who have even a 1% chance of having sex with other people, then PREP is probably a good idea.

      Let me count the number of married people who got HIV from their spouses! 🙄🙄🙄🙄🙄

      • @mjsaber
        6•7 months ago

        I’m not anti gay, I was an STI nurse for a few years. Anal sex for ANYONE carries a higher risk per interaction, regardless of whether you are the receptive or insetive partner.

        My point was not to label all people having unprotected sex as needing PrEP, or only gay people as needing PrEP. My point was to look at the types of sex you have, with the number and types of partners you have, and take a realistic look at what kinds of risks for STI transmission any of those have.

        For instance, if you have lots of unprotected oral sex with strangers, you aren’t going to get HIV. You might get another STI, but HIV is virtually un-transmissable via oral sex. But someone reading the comment might get scared and think they need to take PrEP.

        https://stanfordhealthcare.org/medical-conditions/sexual-and-reproductive-health/hiv-aids/causes/risk-of-exposure.html#:~:text=Therefore%2C unprotected sex with an,exposures)%20for%20receptive%20anal%20sex.

        • @tsonfeir@lemm.ee
          7•7 months ago

          Being a “nurse” doesn’t meant you know anything. I’m married to a nurse and I’m shocked how dumb some of their friends are. You’re giving misleading medical advise, which is a violation. Stop.

          • @mjsaber
            5•7 months ago

            I literally posted a link to an article from Stanford that shows what I’m talking about.

              • @mjsaber
                9•7 months ago

                No, like my initial comment said, number and types of partners are important, as are your partners’ partners.

                If you actually read my comment, you can see I’m trying to get people to look past the stigma and actually determine what kinds of risks they have and make safer sex decisions accordingly.

                PrEP can have some uncomfortable side effects, and not everyone is able to tolerate it. There are very, very few things in healthcare that we can say “everyone” in a certain cohort should do, and PrEP is no exception.

                Your response, which characterizes my post as misinformation, is inaccurate, as I have shown, but I do appreciate the chance to talk about sex and try to normalize it as part of the healthcare discussion 😊

                  • @mjsaber
                    8•7 months ago

                    As long as they aren’t getting medical advice from you, I’m good with it.

      • @ImFresh3x@sh.itjust.works
        2•7 months ago

        It is estimated the risk of HIV transmission through receptive vaginal sex (receiving the penis in the vagina) to be 0.08%.

        Stop rage baiting over basic science. It’s actually harmful to lgbt people to cry anti gay when someone is just stating what doctors are saying about different risks for different types sex.

        https://stanfordhealthcare.org/medical-conditions/sexual-and-reproductive-health/hiv-aids/causes/risk-of-exposure.html

        https://hivrisk.cdc.gov/about-the-data/